Maintenance chrysotherapy in rheumatoid arthritis: a comparison of 2 dose schedules.

Monitoring serum gold values to improve chrysotherapy in rheumatoid arthritis.

Forestier (1929) first used gold salts to treat rheumatoid arthritis (RA), and controlled studies (e.g. Empire Rheumatism Council, 1960, 1961) later confirmed their effectiveness. An empirical schedule of treatment (conventional chrysotherapy) evolved, using 50 mg. monthly, but this might be further improved if dosage could be adjusted for each patient according to the serum level of gold. Atom...

Acute renal failure due to gold.

A patient with rheumatoid arthritis is described who developed acute renal failure whilst receiving gold. This occurred despite the normal precautions of patient monitoring before each dose was given. The clinical picture suggests this was a hypersensitivity reaction to chrysotherapy.

The Effect of Chrysotherapy on the Sedimentation Rate in Rheumatoid Arthritis.

Fatal bronchiolitis obliterans associated with chrysotherapy.

We describe a patient who developed fatal bronchiolitis obliterans following gold therapy and review the relationship between rheumatoid arthritis and bronchiolitis.

Liver Toxicity in Rheumatoid Arthritis Patients Treated With Methotrexate

Background:Methotrexate (MTX) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (RA) which can be associated with toxic effects on different organs. This study was designed to investigate the hepatotoxic effects in RA patients treated with MTX. Methods: In this cross-sectional observational study, RA patients who received standard d...